ECTRIMS 2017: Tanuja Chitnis, MD: Pediatric MS and the PARADIGMS Trial

Tanuja Chitnis, MD, the director of the Partners Pediatric MS Center at Massachusetts General Hospital: So, it was not recognized – it was not well recognized – in the past that children got multiple sclerosis (MS). Many of these children were diagnosed with other disorders or left untreated for many years. It wasn’t until about 2007 when there was the first publication of diagnostic criteria for pediatric MS that it was well recognized, or began to become recognized that children got MS.

[PARADIGMS] is the first study of its kind, and also partly because there weren’t clinical trials being done in this population, with mandates from both the US government as well as the EU through something called the Pediatric Research Equity Act, as well as similar acts within Europe, that there was now a mandate for all new drugs to have a pediatric investigation plan or study done.

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